What is Hemostasis ? - Pathskills

 

                                               Hemostasis

 

 

The hemostasis is defined as the arrestor the stoppage of bleeding don't get confused between hemostasis and Homeostasis

                The homeostasis means the maintenance of the constant internal environment but the hemostasis means hence stasis means stoppage that means arrest or stoppage of the bleeding the hemostasis contains of three stages when the blood vessel is injured the injury initiates a series of reactions that result in the process of hemostasis and it occurs in three stages

Stages

1. the first stage is the vasoconstriction

2.the second stage is the platelet plug formation

3. the third stage is the coagulation of the blood

           so now let's learn about these stages in detail so the process of the hemostasis is firstly initiated due to an injury to the blood vessel that leads to damage of the endothelium this causes the exposure to the collagen and then due to the action of the warn billy band factor the adherence of platelets to the collagen takes place in this adherence of the platelets to the collagen leads to the activation of these platelets then these platelets act in the process of hemostasis that is the vasoconstriction platelet plaque formation

and the coagulation of the blood the stage one is the vasoconstriction and this separation of the serotonin leads to the process of vasoconstriction in the secretion of the adp and thromboxane a2 leads to the aggregation of the platelets by the action of the platelet aggregating factor in this aggregation of platelets lead to the formation of the platelet plug so this is the second stage of the hemostasis and now coming to the third stage the formation of the pro thrombin activator itself lead to the blood clotting so now let's discuss about these steps in detail the stage one is the vasoconstriction so immediately after the injury to the blood vessel the blood vessel constricts and it decreases the loss of blood from the damaged portion the process of vasoconstriction is purely a local phenomena when the blood vessels are cut and the endothelium gets damaged the collagen gets exposed the platelets adhere to this collagen and they get activated the activated platelets secrete serotonin and other vasoconstrictor substances which causes the constriction of the blood vessels an adherence of the platelets to the collagen is accelerated by the bone belly band factor this factor acts as a bridge in between a specific glycoprotein that is present on the surface of the platelet and the collagen fibers so this is the process of vasoconstriction that is the first stage of the process of hemostasis and now coming to the second stage that is the platelet plaque formation the platelets get adhered to the collagen the platelets get adhered to the collagen of the ruptured blood vessels and they secrete and they secrete adenosine diphosphate and the thromboxine a these two substances attract more and more platelets and activate them so all these platelets aggregate together and they form a loose temporary platelet plaque or a temporary hemostatic plaque and this plaque closes the ruptured blood vessels and it prevents the few the blood loss the platelet aggregation is accelerated by the platelet activating factor so this is all about the stage 2 that is the plated plaque formation and now coming to the third stage that is the coagulation of the blood during the process of the coagulation of the blood the fibrinogen is converted into the fibrin and these fibrin threads get attached to the loose platelet plug and this blocks the ruptured part of the blood vessels and it prevents the few the blood loss completely so in this process the ruptured part of the blood vessels blocks and it prevents the few the blood loss completely so this is the third stage that is the coagulation of the blood so guys this is all about the process of the hemostasis